6-(Trifluoromethyl)pyridine-3-carboxaldehyde → 3-(Trifluoromethyl)-6-[4-[[6-(trifluoromethyl)pyridin-3-yl]methyl]piperazin-1-yl]-[1,2,4]triazolo[4,3-a]pyridine

HRID 1146332Notes

Reaction equation

HRID 1146332 reaction equation
[F:20][C:21]([c:22]1[cH:23][cH:24][c:25]([CH:28]=[O:29])[cH:26][n:27]1)([F:30])[F:31].[N:1]1([c:7]2[cH:8][cH:9][c:10]3[n:11]([cH:12]2)[c:13]([C:16]([F:17])([F:18])[F:19])[n:14][n:15]3)[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1>>[N:1]1([c:7]2[cH:8][cH:9][c:10]3[n:11]([cH:12]2)[c:13]([C:16]([F:17])([F:18])[F:19])[n:14][n:15]3)[CH2:2][CH2:3][N:4]([CH2:28][c:25]2[cH:24][cH:23][c:22]([C:21]([F:20])([F:30])[F:31])[n:27][cH:26]2)[CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 27777626-(Trifluoromethyl)pyridine-3-carboxaldehydeHCID 673412226-(Piperazin-1-yl)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine

Product 1

HCID 866380683-(Trifluoromethyl)-6-[4-[[6-(trifluoromethyl)pyridin-3-yl]methyl]piperazin-1-yl]-[1,2,4]triazolo[4,3-a]pyridine

Sources & evidence

ORD record
ord-ad0f6428dd124505bb9db129b5e3449a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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