Ammonium → methyl 2-(5-hydroxy-1H-indol-1-yl)propanoate

HRID 114638Notes

Reaction equation

HRID 114638 reaction equation
[CH2:32]([OH:33])[CH3:34].[CH3:1][O:2][C:3]([CH:4]([CH3:5])[n:6]1[cH:7][cH:8][c:9]2[cH:10][c:11]([O:15][CH2:16][c:17]3[cH:18][cH:19][cH:20][cH:21][cH:22]3)[cH:12][cH:13][c:14]12)=[O:23].[CH3:28][CH2:29][OH:30].[CH:24]([O-:25])=[O:26].[NH4+:27].[OH-:35].[OH-:37].[OH2:31].[Pd+2:36]>>[CH3:1][O:2][C:3]([CH:4]([CH3:5])[n:6]1[cH:7][cH:8][c:9]2[cH:10][c:11]([OH:15])[cH:12][cH:13][c:14]12)=[O:23]

Participants

8

Reactant 7

HCID 223AmmoniumHCID 283FormateHCID 702Ethanol2×HCID 961Hydroxide2×HCID 962WaterHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 578454965-Benzyloxy-indol-1-yl-propionic acid methyl ester

Product 1

HCID 57845447methyl 2-(5-hydroxy-1H-indol-1-yl)propanoate

Sources & evidence

ORD record
ord-0360b14de5374d9bbe9ce83f09e20be3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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