(Pyrimidin-5-yl)boronic acid → N,N-dimethyl-4-((4-morpholino-2-(pyrimidin-5-yl)thieno[2,3-d]pyrimidin-6-yl)methyl)piperazine-1-carboxamide
Reaction equation
[Cl:1][c:2]1[n:3][c:4]([N:23]2[CH2:24][CH2:25][O:26][CH2:27][CH2:28]2)[c:5]2[c:6]([n:7]1)[s:8][c:9]([CH2:11][N:12]1[CH2:13][CH2:14][N:15]([C:18](=[O:19])[N:20]([CH3:21])[CH3:22])[CH2:16][CH2:17]1)[cH:10]2.[n:29]1[cH:30][n:31][cH:32][c:33]([B:35]([OH:36])[OH:37])[cH:34]1>>[c:2]1(-[c:33]2[cH:32][n:31][cH:30][n:29][cH:34]2)[n:3][c:4]([N:23]2[CH2:24][CH2:25][O:26][CH2:27][CH2:28]2)[c:5]2[c:6]([n:7]1)[s:8][c:9]([CH2:11][N:12]1[CH2:13][CH2:14][N:15]([C:18](=[O:19])[N:20]([CH3:21])[CH3:22])[CH2:16][CH2:17]1)[cH:10]2Participants
3
Sources & evidence
- ORD record
- ord-df95d530edd34a1e823819b99992d64d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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