Pyridine → 4-{N-[2-(4-Fluoro-phenyl)-acetyl]-N'-methyl-N'-(2-methylsulfanyl-pyrimidine-4-carbonyl)-hydrazino}-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([NH:14][N:15]([C:16](=[O:17])[c:18]2[n:19][c:20]([S:24][CH3:25])[n:21][cH:22][cH:23]2)[CH3:26])[CH2:12][CH2:13]1.[F:27][c:28]1[cH:29][cH:30][c:31]([CH2:34][C:35](=[O:36])[Cl:37])[cH:32][cH:33]1.[cH:38]1[cH:39][cH:40][n:41][cH:42][cH:43]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([N:14]([N:15]([C:16](=[O:17])[c:18]2[n:19][c:20]([S:24][CH3:25])[n:21][cH:22][cH:23]2)[CH3:26])[C:35]([CH2:34][c:31]2[cH:30][cH:29][c:28]([F:27])[cH:33][cH:32]2)=[O:36])[CH2:12][CH2:13]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-8db923ef714f4053abbacff2bc20525c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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