Acetate → 4-[3-Tert-butyl-5-(1,1-dimethoxyethyl)-2-methoxyphenyl]morpholine

HRID 1146728Notes

Reaction equation

HRID 1146728 reaction equation
[Br:1][c:2]1[c:3]([O:18][CH3:19])[c:4]([C:14]([CH3:15])([CH3:16])[CH3:17])[cH:5][c:6]([C:8]([CH3:9])([O:10][CH3:11])[O:12][CH3:13])[cH:7]1.[C:38]([O-:39])(=[O:40])[CH3:41].[C:43]([O-:44])(=[O:45])[CH3:46].[CH2:20]1[CH2:21][O:22][CH2:23][CH2:24][NH:25]1.[CH3:26][C:27]([CH3:28])([O-:29])[CH3:30].[CH3:32][O:33][CH2:34][CH2:35][O:36][CH3:37].[Na+:31].[Pd+2:42]>>[c:2]1([N:25]2[CH2:20][CH2:21][O:22][CH2:23][CH2:24]2)[c:3]([O:18][CH3:19])[c:4]([C:14]([CH3:15])([CH3:16])[CH3:17])[cH:5][c:6]([C:8]([CH3:9])([O:10][CH3:11])[O:12][CH3:13])[cH:7]1

Participants

8

Reactant 7

HCID 175Acetate2×HCID 923Sodium ionHCID 80711,2-DimethoxyethaneHCID 8083MorpholineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 45749132-Methylpropan-2-olateHCID 230937191-Bromo-3-tert-butyl-5-(1,1-dimethoxyethyl)-2-methoxybenzene

Product 1

HCID 230937244-[3-Tert-butyl-5-(1,1-dimethoxyethyl)-2-methoxyphenyl]morpholine

Sources & evidence

ORD record
ord-26b5c0911c3e48eca519a0c1fc292692
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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