Pyridine → 4-{2-[2-(4-Chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-acetylamino}-3,5-difluoro-benzoic acid methyl ester
Reaction equation
[CH2:1]([O:2][C:3](=[O:4])[c:5]1[cH:6][cH:7][c:8]([NH:9][C:12]([CH:13]([CH:14]2[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19]2)[n:20]2[c:21](-[c:31]3[cH:32][cH:33][c:34]([Cl:37])[cH:35][cH:36]3)[n:22][c:23]3[c:24]2[cH:25][c:26]([F:30])[c:27]([F:29])[cH:28]3)=[O:38])[cH:10][cH:11]1)[CH3:39].[CH3:68][O:69][C:70]([c:71]1[cH:72][c:73]([F:79])[c:74]([NH2:78])[c:75]([F:77])[cH:76]1)=[O:80].[Cl:40][c:41]1[cH:42][cH:43][c:44](-[c:45]2[n:46]([CH:47]([CH:48]3[CH2:49][CH2:50][CH2:51][CH2:52][CH2:53]3)[C:54]([OH:55])=[O:56])[c:57]3[cH:58][c:59]([F:60])[c:61]([F:62])[cH:63][c:64]3[n:65]2)[cH:66][cH:67]1.[cH:81]1[cH:82][cH:83][n:84][cH:85][cH:86]1>>[C:12]([CH:13]([CH:14]1[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19]1)[n:20]1[c:21](-[c:31]2[cH:32][cH:33][c:34]([Cl:37])[cH:35][cH:36]2)[n:22][c:23]2[c:24]1[cH:25][c:26]([F:30])[c:27]([F:29])[cH:28]2)(=[O:38])[NH:78][c:74]1[c:73]([F:79])[cH:72][c:71]([C:70]([O:69][CH3:68])=[O:80])[cH:76][c:75]1[F:77]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-4b51ca984a9c4296928cacba8ab35a18
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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