Methanol → 4-((Tert-butyldimethylsilyl)oxy)piperidine

HRID 1147251Notes

Reaction equation

HRID 1147251 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][CH:11]([O:14][Si:15]([CH3:16])([CH3:17])[C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:12][CH2:13]1.[CH3:27][OH:28].[H:22][H:23].[OH-:24].[OH-:26].[Pd+2:25]>>[NH:8]1[CH2:9][CH2:10][CH:11]([O:14][Si:15]([CH3:16])([CH3:17])[C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 887MethanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 57588941HCID 57588941, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 114813284-((Tert-butyldimethylsilyl)oxy)piperidine

Sources & evidence

ORD record
ord-d93a3c4d89ea4b0a8fbac1ed9a3946f3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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