2-{[4-(Hydroxymethyl)phenoxy]methyl}oxirane → 1-(4-(Hydroxymethyl)phenoxy)-3-(1-(5-phenylthieno[2,3-d]pyrimidin-4-yl)piperidin-4-ylamino)propan-2-ol

HRID 1147266Notes

Reaction equation

HRID 1147266 reaction equation
[O:1]1[CH:2]([CH2:4][O:5][c:6]2[cH:7][cH:8][c:9]([CH2:12][OH:13])[cH:10][cH:11]2)[CH2:3]1.[c:14]1(-[c:20]2[cH:21][s:22][c:23]3[n:24][cH:25][n:26][c:27]([N:29]4[CH2:30][CH2:31][CH:32]([NH2:35])[CH2:33][CH2:34]4)[c:28]23)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[OH:1][CH:2]([CH2:3][NH:35][CH:32]1[CH2:31][CH2:30][N:29]([c:27]2[n:26][cH:25][n:24][c:23]3[s:22][cH:21][c:20](-[c:14]4[cH:15][cH:16][cH:17][cH:18][cH:19]4)[c:28]32)[CH2:34][CH2:33]1)[CH2:4][O:5][c:6]1[cH:7][cH:8][c:9]([CH2:12][OH:13])[cH:10][cH:11]1

Participants

3

Reactant 2

HCID 248237062-{[4-(Hydroxymethyl)phenoxy]methyl}oxiraneHCID 690415621-(5-Phenylthieno[2,3-d]pyrimidin-4-yl)piperidin-4-amine

Product 1

HCID 249371401-(4-(Hydroxymethyl)phenoxy)-3-(1-(5-phenylthieno[2,3-d]pyrimidin-4-yl)piperidin-4-ylamino)propan-2-ol

Sources & evidence

ORD record
ord-b294f681acff4a5abfdfb2285babc1f3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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