Dimethyl Sulfoxide → N-(4-Pentafluoroethyl-phenyl)-2-[(pyrimidin-4-ylmethyl)-amino]-nicotinamide
Reaction equation
[BH4-:32].[CH3:34][S:35]([CH3:36])=[O:37].[NH2:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][c:7]2[cH:8][cH:9][c:10]([C:13]([C:14]([F:15])([F:16])[F:17])([F:18])[F:19])[cH:11][cH:12]2)[cH:20][cH:21][cH:22][n:23]1.[Na+:33].[n:24]1[cH:25][n:26][c:27]([CH:30]=[O:31])[cH:28][cH:29]1>>[NH:1]([c:2]1[c:3]([C:4](=[O:5])[NH:6][c:7]2[cH:8][cH:9][c:10]([C:13]([C:14]([F:15])([F:16])[F:17])([F:18])[F:19])[cH:11][cH:12]2)[cH:20][cH:21][cH:22][n:23]1)[CH2:30][c:27]1[n:26][cH:25][n:24][cH:29][cH:28]1Participants
6
Sources & evidence
- ORD record
- ord-01dc5be195b64a168bb037a51ecd26c1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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