5'-(5,5-Dimethyl-[1,3,2]dioxaborinan-2-yl)-5,2'-difluorobiphenyl-2-carbonitrile → 5,2'-Difluoro-5'-(7-trifluoromethyl-[1,8]naphthyridin-4-yl)biphenyl-2-carbonitrile

HRID 1147519Notes

Reaction equation

HRID 1147519 reaction equation
[CH3:16][C:17]1([CH3:18])[CH2:19][O:20][B:21]([c:23]2[cH:24][cH:25][c:26]([F:38])[c:27](-[c:29]3[c:30]([C:36]#[N:37])[cH:31][cH:32][c:33]([F:35])[cH:34]3)[cH:28]2)[O:22][CH2:39]1.[Cl:1][c:2]1[c:3]2[cH:4][cH:5][c:6]([C:12]([F:13])([F:14])[F:15])[n:7][c:8]2[n:9][cH:10][cH:11]1>>[c:2]1(-[c:23]2[cH:24][cH:25][c:26]([F:38])[c:27](-[c:29]3[c:30]([C:36]#[N:37])[cH:31][cH:32][c:33]([F:35])[cH:34]3)[cH:28]2)[c:3]2[cH:4][cH:5][c:6]([C:12]([F:13])([F:14])[F:15])[n:7][c:8]2[n:9][cH:10][cH:11]1

Participants

3

Reactant 2

HCID 116884435'-(5,5-Dimethyl-[1,3,2]dioxaborinan-2-yl)-5,2'-difluorobiphenyl-2-carbonitrileHCID 222852765-chloro-2-(trifluoromethyl)-1,8-Naphthyridine

Product 1

HCID 101363065,2'-Difluoro-5'-(7-trifluoromethyl-[1,8]naphthyridin-4-yl)biphenyl-2-carbonitrile

Sources & evidence

ORD record
ord-e24809f552f7449c9dfece5aedb58d20
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…