2,6-Dichloropyrazine → Tert-butyl 4-(6-chloropyrazin-2-ylamino)piperidine-1-carboxylate

HRID 1147545Notes

Reaction equation

HRID 1147545 reaction equation
[Cl:1][c:2]1[n:3][c:4]([Cl:8])[cH:5][n:6][cH:7]1.[Cl:23][c:24]1[n:25][c:26]([N:27]2[CH2:28][CH2:29][N:30]([C:31]([O:32][C:33]([CH3:34])([CH3:35])[CH3:36])=[O:37])[CH2:38][CH2:39]2)[cH:40][n:41][cH:42]1.[NH2:9][CH:10]1[CH2:11][CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]1>>[c:2]1([NH:9][CH:10]2[CH2:11][CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]2)[n:3][c:4]([Cl:8])[cH:5][n:6][cH:7]1

Participants

4

Reactant 3

HCID 785042,6-DichloropyrazineHCID 12682914-Amino-1-Boc-piperidineHCID 18186946Tert-butyl 4-(6-chloropyrazin-2-YL)piperazine-1-carboxylate

Product 1

HCID 53486077Tert-butyl 4-(6-chloropyrazin-2-ylamino)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-73983802bde64bd9acd29e58bcee0b0f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…