Pyridine → t-butyl (RS)-4-[4-(5-methoxymethyl-2-oxo-oxazolidin-3-yl)-phenyl]-piperidine-1-carboxylate

HRID 1147718Notes

Reaction equation

HRID 1147718 reaction equation
[CH2:1]([O:2][C:3](=[O:4])[NH:6][c:7]1[cH:8][cH:9][c:10]([CH:13]2[CH2:14][CH2:15][N:16]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:17][CH2:18]2)[cH:11][cH:12]1)[CH3:5].[CH3:26][O:27][CH2:28][CH:29]1[O:30][C:31](=[O:34])[O:32][CH2:33]1.[cH:35]1[cH:36][cH:37][n:38][cH:39][cH:40]1>>[N:6]1([c:7]2[cH:8][cH:9][c:10]([CH:13]3[CH2:14][CH2:15][N:16]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:17][CH2:18]3)[cH:11][cH:12]2)[C:31](=[O:34])[O:30][CH:29]([CH2:28][O:27][CH3:26])[CH2:33]1

Participants

4

Reactant 3

HCID 1049PyridineHCID 43844854-(Methoxymethyl)-1,3-dioxolan-2-oneHCID 23371871t-Butyl 4-(4-ethoxycarbonylamino-phenyl)-piperidine-1-carboxylate

Product 1

HCID 86749979t-butyl (RS)-4-[4-(5-methoxymethyl-2-oxo-oxazolidin-3-yl)-phenyl]-piperidine-1-carboxylate

Sources & evidence

ORD record
ord-8e6f5478278c4b8f9c3965433c69d91b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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