HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1147725Generated: October 31, 2026
Isopropanol → 5,6-difluoro-N-(4-(3-(2-(4-(4-methylpiperazin-1-yl)phenylamino)pyrimidin-4-yl)pyridin-2-yloxy)phenyl)-1H-benzo[d]imidazol-2-amine
https://huagongshe.com/reaction/1147725
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 4-(4-Methylpiperazin-1-yl)aniline | HCID 737253 | — |
| Reactant | 5,6-difluoro-N-(4-(3-(2-(methylsulfonyl)pyrimidin-4-yl)pyridin-2-yloxy)phenyl)-1H-benzo[d]imidazol-2-amine | HCID 66862953 | — |
| Product | 5,6-difluoro-N-(4-(3-(2-(4-(4-methylpiperazin-1-yl)phenylamino)pyrimidin-4-yl)pyridin-2-yloxy)phenyl)-1H-benzo[d]imidazol-2-amine | HCID 58966968 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (7/10) |
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| ORD ID | ord-fc6f4f8916a7484d8d84de8b7c54a519 |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (7/10) |
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