Ammonium → 1-(2-(6-hydroxy-2-pyridin-2-yl-3-(2-trimethylsilanyl-ethoxymethyl)-3H-benzimidazol-5-yl)-pyrrolidin-1-yl)-ethanone

HRID 1147758Notes

Reaction equation

HRID 1147758 reaction equation
[C+4:44].[CH2:5]([c:6]1[cH:7][cH:8][cH:9][cH:10][cH:11]1)[O:12][c:13]1[c:14]([CH:36]2[N:37]([C:41]([CH3:42])=[O:43])[CH2:38][CH2:39][CH2:40]2)[cH:15][c:16]2[c:17]([n:18][c:19](-[c:29]3[n:30][cH:31][cH:32][cH:33][cH:34]3)[n:20]2[CH2:21][O:22][CH2:23][CH2:24][Si:25]([CH3:26])([CH3:27])[CH3:28])[cH:35]1.[CH3:52][CH2:53][OH:54].[CH:1]([O-:2])=[O:3].[NH4+:4].[OH-:45].[OH-:47].[OH-:48].[OH-:49].[OH-:50].[OH-:51].[Pd+2:46]>>[OH:12][c:13]1[c:14]([CH:36]2[N:37]([C:41]([CH3:42])=[O:43])[CH2:38][CH2:39][CH2:40]2)[cH:15][c:16]2[c:17]([n:18][c:19](-[c:29]3[n:30][cH:31][cH:32][cH:33][cH:34]3)[n:20]2[CH2:21][O:22][CH2:23][CH2:24][Si:25]([CH3:26])([CH3:27])[CH3:28])[cH:35]1

Participants

8

Reactant 7

HCID 223AmmoniumHCID 283FormateHCID 702EthanolHCID 961Hydroxide6×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 231455661-(2-(6-benzyloxy-2-pyridin-2-yl-3-(2-trimethylsilanyl-ethoxymethyl)-3H-benzimidazol-5-yl)-pyrrolidin-1-yl)-ethanoneHCID 178420935HCID 178420935, compound

Product 1

HCID 231452771-(2-(6-hydroxy-2-pyridin-2-yl-3-(2-trimethylsilanyl-ethoxymethyl)-3H-benzimidazol-5-yl)-pyrrolidin-1-yl)-ethanone

Sources & evidence

ORD record
ord-63c0392f2618456aab90d435f7316f08
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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