Tert-butyl 4-(2-pyrrolidin-1-ylacetyl)piperidinecarboxylate → 4-(N-tert-butoxycarbonyl-2-chloro-4-fluorobenzylamino)-6-cyclopropylcarbonyl-2-[4-(2-pyrrolidin-1-ylacetyl)piperidino]-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]([c:9]1[c:10]2[c:11]([n:12][c:13]([Cl:15])[n:14]1)[CH2:16][CH2:17][N:18]([C:20](=[O:21])[CH:22]1[CH2:23][CH2:24]1)[CH2:19]2)[CH2:25][c:26]1[c:27]([Cl:33])[cH:28][c:29]([F:32])[cH:30][cH:31]1.[N:34]1([CH2:39][C:40](=[O:41])[CH:42]2[CH2:43][CH2:44][N:45]([C:48]([O:49][C:50]([CH3:51])([CH3:52])[CH3:53])=[O:54])[CH2:46][CH2:47]2)[CH2:35][CH2:36][CH2:37][CH2:38]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]([c:9]1[c:10]2[c:11]([n:12][c:13]([N:45]3[CH2:44][CH2:43][CH:42]([C:40]([CH2:39][N:34]4[CH2:35][CH2:36][CH2:37][CH2:38]4)=[O:41])[CH2:47][CH2:46]3)[n:14]1)[CH2:16][CH2:17][N:18]([C:20](=[O:21])[CH:22]1[CH2:23][CH2:24]1)[CH2:19]2)[CH2:25][c:26]1[c:27]([Cl:33])[cH:28][c:29]([F:32])[cH:30][cH:31]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-2c7ae01bf3a74e64a18e003c9880a07e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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