Sodium ion → 1-Benzyl-3-(3,4-difluorophenyl)pyrrolidin-3-ol
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([F:9])[c:5]([F:8])[cH:6][cH:7]1.[CH2:10]([Li:11])[CH2:12][CH2:13][CH3:14].[CH2:15]([c:16]1[cH:17][cH:18][cH:19][cH:20][cH:21]1)[N:22]1[CH2:23][C:24](=[O:27])[CH2:25][CH2:26]1.[CH3:34][CH2:35][O:36][CH2:37][CH3:38].[Na+:28].[Na+:29].[O-:30][C:31](=[O:32])[O-:33]>>[c:2]1([C:24]2([OH:27])[CH2:23][N:22]([CH2:15][c:16]3[cH:17][cH:18][cH:19][cH:20][cH:21]3)[CH2:26][CH2:25]2)[cH:3][c:4]([F:9])[c:5]([F:8])[cH:6][cH:7]1Participants
7
Sources & evidence
- ORD record
- ord-0df3bfb38a9e4159ba804a350686b98c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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