Methanol → Methyl 2-bromo-5-fluoropyridine-4-carboxylate

HRID 1148118Notes

Reaction equation

HRID 1148118 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[OH:7])[c:8]([F:11])[cH:9][n:10]1.[CH3:16][OH:17].[Cl:12][S:13](=[O:14])[Cl:15]>>[Br:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[O:7][CH3:16])[c:8]([F:11])[cH:9][n:10]1

Participants

4

Reactant 3

HCID 887MethanolHCID 24386Thionyl ChlorideHCID 467392772-Bromo-5-fluoroisonicotinic acid

Product 1

HCID 46311206Methyl 2-bromo-5-fluoropyridine-4-carboxylate

Sources & evidence

ORD record
ord-8e7d13ab0039402d821660db2b43c6e2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…