Dichloromethane → 5',7'-dimethyl-1'-(quinolin-2-ylmethyl)-3',4'-dihydro-1'H-spiro[cyclobutane-1,2'-quinolin]-6'-ol
Reaction equation
[B:29]([Br:30])([Br:31])[Br:32].[CH3:1][O:2][c:3]1[c:4]([CH3:28])[c:5]2[c:13]([cH:14][c:15]1[CH3:16])[N:12]([CH2:17][c:18]1[n:19][c:20]3[cH:21][cH:22][cH:23][cH:24][c:25]3[cH:26][cH:27]1)[C:8]1([CH2:7][CH2:6]2)[CH2:9][CH2:10][CH2:11]1.[Cl:33][CH2:34][Cl:35]>>[OH:2][c:3]1[c:4]([CH3:28])[c:5]2[c:13]([cH:14][c:15]1[CH3:16])[N:12]([CH2:17][c:18]1[n:19][c:20]3[cH:21][cH:22][cH:23][cH:24][c:25]3[cH:26][cH:27]1)[C:8]1([CH2:7][CH2:6]2)[CH2:9][CH2:10][CH2:11]1Participants
4
Sources & evidence
- ORD record
- ord-4d1f684dc17b4c9298a36bce874700a2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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