Methanol → 1,1,1-trifluoro-2-(piperidin-4-yl)propan-2-ol
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][CH:11]([C:14]([C:15]([F:16])([F:17])[F:18])([CH3:19])[OH:20])[CH2:12][CH2:13]1.[CH3:21][OH:22]>>[NH:8]1[CH2:9][CH2:10][CH:11]([C:14]([C:15]([F:16])([F:17])[F:18])([CH3:19])[OH:20])[CH2:12][CH2:13]1Participants
3
Sources & evidence
- ORD record
- ord-55989813ce8545408ba7e6ecd3aeae5c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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