Trimethyl borate → 5-Chloro-2-methoxyphenylboronic acid

HRID 1148543Notes

Reaction equation

HRID 1148543 reaction equation
[Br:13][c:14]1[cH:15][c:16]([Cl:20])[cH:17][cH:18][c:19]1[O:21][CH3:22].[CH3:23][CH2:24][CH2:25][CH2:26][Li:27].[CH3:28][O:29][B:30]([O:31][CH3:32])[O:33][CH3:34].[F:1][c:2]1[cH:3][cH:4][c:5]([O:11][CH3:12])[c:6]([B:8]([OH:9])[OH:10])[cH:7]1>>[c:2]1([Cl:20])[cH:3][cH:4][c:5]([O:11][CH3:12])[c:6]([B:8]([OH:9])[OH:10])[cH:7]1

Participants

5

Reactant 4

HCID 8470Trimethyl borateHCID 5219352-Bromo-4-chloroanisoleHCID 27826735-Fluoro-2-methoxyphenylboronic acidHCID 178418339Butyllithium

Product 1

HCID 27357515-Chloro-2-methoxyphenylboronic acid

Sources & evidence

ORD record
ord-acd7bd9f48394146b04425b3bdac4052
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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