反应详情

温度

200 °C

A flask is loaded with (17) (21.5 g, 0.1 mol), 4-fluoroacetophenone (13.8 g, 0.1 mol), and toluene sulfonic acid monohydrate (3.8 g, 0.02 mol). The flask is heated to 200° C. and the water of condensation removed. After water evolution ceased, the mixture is cooled and the crude solid product is crushed and washed with hot ethanol The product is further recrystallized from toluene.

1. customremoved
2. temperaturethe mixture is cooled
3. customthe crude solid product is crushed
4. washwashed with hot ethanol The product
5. customis further recrystallized from toluene