tert-Butyl (3-amino-2'-fluoro-[1,1'-biphenyl]-4-yl)carbamate → {3-[3-(5-Cyano-2-fluoro-phenyl)-3-oxo-propionylamino]-2'-fluoro-biphenyl-4-yl}-carbamic acid tert.-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH2:21])[cH:10][c:11](-[c:14]2[c:15]([F:20])[cH:16][cH:17][cH:18][cH:19]2)[cH:12][cH:13]1)=[O:22].[CH2:23]([O:25][C:26](=[O:24])[CH2:27][C:28](=[O:29])[c:30]1[c:31]([F:38])[cH:32][cH:33][c:34]([C:36]#[N:37])[cH:35]1)[CH3:39]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH:21][C:26](=[O:25])[CH2:27][C:28](=[O:29])[c:30]2[c:31]([F:38])[cH:32][cH:33][c:34]([C:36]#[N:37])[cH:35]2)[cH:10][c:11](-[c:14]2[c:15]([F:20])[cH:16][cH:17][cH:18][cH:19]2)[cH:12][cH:13]1)=[O:22]Participants
3
Sources & evidence
- ORD record
- ord-faf1850108194c1093b47d1b54de2fdd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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