4-(4-Amino-3-fluorophenyl)morpholin-3-one → 3-{[(5-Chloro-thiophene-2-carbonyl)-amino]-methyl}-[1,2,4]oxadiazole-5-carboxylic acid [2-fluoro-4-(3-oxo-morpholin-4-yl)-phenyl]-amide

HRID 114931Notes

Reaction equation

HRID 114931 reaction equation
[CH2:1]([O:2][C:4](=[O:5])[c:6]1[n:7][c:8]([CH2:11][NH:12][C:13](=[O:14])[c:15]2[s:16][c:17]([Cl:20])[cH:18][cH:19]2)[n:9][o:10]1)[CH3:3].[NH2:21][c:22]1[c:23]([F:35])[cH:24][c:25]([N:28]2[C:29](=[O:34])[CH2:30][O:31][CH2:32][CH2:33]2)[cH:26][cH:27]1>>[C:4](=[O:5])([c:6]1[n:7][c:8]([CH2:11][NH:12][C:13](=[O:14])[c:15]2[s:16][c:17]([Cl:20])[cH:18][cH:19]2)[n:9][o:10]1)[NH:21][c:22]1[c:23]([F:35])[cH:24][c:25]([N:28]2[C:29](=[O:34])[CH2:30][O:31][CH2:32][CH2:33]2)[cH:26][cH:27]1

Participants

3

Reactant 2

HCID 534177984-(4-Amino-3-fluorophenyl)morpholin-3-oneHCID 593029563-{[(5-Chloro-thiophene-2-carbonyl)-amino]-methyl}-[1,2,4]oxadiazole-5-carboxylic acid ethyl ester

Product 1

HCID 249676313-{[(5-Chloro-thiophene-2-carbonyl)-amino]-methyl}-[1,2,4]oxadiazole-5-carboxylic acid [2-fluoro-4-(3-oxo-morpholin-4-yl)-phenyl]-amide

Sources & evidence

ORD record
ord-2e228e390d9f4a2c9cad530b8b972544
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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