Bicarbonate Ion → 2-(4-Fluorophenyl)-3-iodo-7,8-dimethyl-6-piperazin-1-ylimidazo[1,2-b]pyridazine
Reaction equation
[C:34](=[O:35])([O-:36])[OH:37].[CH3:42][OH:43].[Cl:39][CH2:40][Cl:41].[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([n:12][c:13]([N:18]4[CH2:19][CH2:20][NH:21][CH2:22][CH2:23]4)[c:14]([CH3:17])[c:15]3[CH3:16])[cH:24]2)[cH:6][cH:7]1.[I:25][Cl:26].[Na+:32].[Na+:33].[Na+:38].[S:27]([O-:28])([O-:29])(=[O:30])=[S:31]>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([n:12][c:13]([N:18]4[CH2:19][CH2:20][NH:21][CH2:22][CH2:23]4)[c:14]([CH3:17])[c:15]3[CH3:16])[c:24]2[I:25])[cH:6][cH:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-48caac9c460e43d8b09e4142c65c2234
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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