1-Pyrrolidineethanamine → N-(3-chloro-2-fluorophenyl)-7-methoxy-6-{[(2-pyrrolidin-1-ylethyl)amino]methyl}quinazolin-4-amine
Reaction equation
[Cl:1][c:2]1[c:3]([F:23])[c:4]([NH:5][c:6]2[n:7][cH:8][n:9][c:10]3[cH:11][c:12]([O:18][CH3:19])[c:13]([CH:16]=[O:17])[cH:14][c:15]23)[cH:20][cH:21][cH:22]1.[N:24]1([CH2:29][CH2:30][NH2:31])[CH2:25][CH2:26][CH2:27][CH2:28]1>>[Cl:1][c:2]1[c:3]([F:23])[c:4]([NH:5][c:6]2[n:7][cH:8][n:9][c:10]3[cH:11][c:12]([O:18][CH3:19])[c:13]([CH2:16][NH:31][CH2:30][CH2:29][N:24]4[CH2:25][CH2:26][CH2:27][CH2:28]4)[cH:14][c:15]23)[cH:20][cH:21][cH:22]1Participants
3
Sources & evidence
- ORD record
- ord-361e60246f604856811927321d2fab95
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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