2-Amino-3,5-dibromopyrazine → 5-Bromo-3-[1-(2-chloro-3,6-difluoro-phenyl)-ethoxy]-pyrazin-2-ylamine

HRID 1149827Notes

Reaction equation

HRID 1149827 reaction equation
[Br:13][c:14]1[c:15]([NH2:21])[n:16][cH:17][c:18]([Br:20])[n:19]1.[Cl:1][c:2]1[c:3]([CH:10]([CH3:11])[OH:12])[c:4]([F:9])[cH:5][cH:6][c:7]1[F:8]>>[Cl:1][c:2]1[c:3]([CH:10]([CH3:11])[O:12][c:14]2[c:15]([NH2:21])[n:16][cH:17][c:18]([Br:20])[n:19]2)[c:4]([F:9])[cH:5][cH:6][c:7]1[F:8]

Participants

3

Reactant 2

HCID 6200042-Amino-3,5-dibromopyrazineHCID 211113742-Chloro-3,6-difluoro-α-methylbenzenemethanol

Product 1

HCID 211114825-Bromo-3-[1-(2-chloro-3,6-difluoro-phenyl)-ethoxy]-pyrazin-2-ylamine

Sources & evidence

ORD record
ord-58d01c83141a4a5f909701a254f4b412
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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