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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1149924Generated: November 1, 2026

Dichloromethane → 4-Chloro-7-(2-fluoro-4-methylsulfonylphenyl)-6-methyl-5,6-dihydropyrrolo[2,3-d]pyrimidine

https://huagongshe.com/reaction/1149924

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTriethylamineHCID 8471—
ReactantMethanesulfonic anhydrideHCID 81560—
Reactant1-[4-Chloro-6-(2-fluoro-4-methylsulfonylanilino)pyrimidin-5-yl]propan-2-olHCID 71540212—
ReactantN-[6-chloro-5-[2-[(methylsulfonyl)oxy]ethyl]-4-pyrimidinyl]-N-[2-fluoro-4-(methylsulfonyl)phenyl]Carbamic acid 1,1-dimethylethyl esterHCID 86637380—
Product4-Chloro-7-(2-fluoro-4-methylsulfonylphenyl)-6-methyl-5,6-dihydropyrrolo[2,3-d]pyrimidineHCID 71540213—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-62acffb65d0f45579d7d3fa97746581f
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)