Ethyl 3-methyl-5-(2-oxo-3-(4-(trifluoromethyl)benzyl)imidazolidin-1-yl)thiophene-2-carboxylate → 2-(3-(4-fluorobenzyl)-2-oxotetrahydropyrimidin-1(2H)-yl)-4-methylthiazole-5-carboxylic acid
Reaction equation
[CH3:1][c:2]1[cH:3][c:4]([N:5]2[CH2:6][CH2:7][N:8]([CH2:9][c:10]3[cH:11][cH:12][c:13]([C:14]([F:15])([F:16])[F:17])[cH:18][cH:19]3)[C:20]2=[O:21])[s:22][c:23]1[C:24]([O:25][CH2:26][CH3:27])=[O:28].[F:29][c:30]1[cH:31][cH:32][c:33]([CH2:34][N:35]2[C:36](=[O:52])[N:37]([c:41]3[s:42][c:43]([C:47](=[O:48])[O:49][CH2:50][CH3:51])[c:44]([CH3:46])[n:45]3)[CH2:38][CH2:39][CH2:40]2)[cH:53][cH:54]1>>[F:29][c:30]1[cH:31][cH:32][c:33]([CH2:34][N:35]2[C:36](=[O:52])[N:37]([c:41]3[s:42][c:43]([C:47](=[O:48])[OH:49])[c:44]([CH3:46])[n:45]3)[CH2:38][CH2:39][CH2:40]2)[cH:53][cH:54]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-582bc3da87e745cdab0bcd0d607220d2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
Loading…