Acetone → 5-Methyl-2-(4-[(-2-[2,2,2-trifluoroethyl]guanidino)thiazol-4-yl]butylamino)pyrimid-4-one
Reaction equation
[CH3:46][C:47](=[O:48])[CH3:49].[F:1][C:2]([CH2:3][N:4]=[C:5]([NH:6][c:7]1[s:8][cH:9][c:10]([CH2:12][CH2:13][CH2:14][CH2:15][NH2:16])[n:11]1)[NH2:17])([F:18])[F:19].[N+:20]([NH:21][c:24]1[n:25][cH:26][c:27]([CH3:31])[c:28](=[O:30])[nH:29]1)([O-:22])=[O:23].[OH:32][C:33]([CH:34]=[CH:35][C:36](=[O:37])[OH:38])=[O:39].[cH:40]1[cH:41][cH:42][n:43][cH:44][cH:45]1>>[F:1][C:2]([CH2:3][N:4]=[C:5]([NH:6][c:7]1[s:8][cH:9][c:10]([CH2:12][CH2:13][CH2:14][CH2:15][NH:16][c:24]2[n:25][cH:26][c:27]([CH3:31])[c:28](=[O:30])[nH:29]2)[n:11]1)[NH2:17])([F:18])[F:19]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-04008b0da6d04fde9176b09952264a11
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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