Methanol → 1-[2,3-Difluoro-4-(5-fluoropyridin-2-yl)phenyl]-2,2-difluoroethanone
Reaction equation
[CH3:31][OH:32].[F:3][c:4]1[c:5]([C:18]([C:19]([F:20])([F:21])[P:22](=[O:23])([O:24][CH2:25][CH3:26])[O:27][CH2:28][CH3:29])=[O:30])[cH:6][cH:7][c:8](-[c:11]2[n:12][cH:13][c:14]([F:17])[cH:15][cH:16]2)[c:9]1[F:10].[Na+:2].[OH-:1]>>[F:3][c:4]1[c:5]([C:18]([CH:19]([F:20])[F:21])=[O:30])[cH:6][cH:7][c:8](-[c:11]2[n:12][cH:13][c:14]([F:17])[cH:15][cH:16]2)[c:9]1[F:10]Participants
5
Sources & evidence
- ORD record
- ord-00c019ff61f6425087a268e7c5c3b717
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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