3-Methoxy-4-(1-methylpiperidin-4-yl)aniline → [3-Methoxy-4-(1-methyl-piperidin-4-yl)-phenyl]-[7-(6-methoxy-pyridin-3-yl)-pyrrolo[2,1-f][1,2,4]triazin-2-yl]-amine

HRID 115068Notes

Reaction equation

HRID 115068 reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[cH:10][cH:11][c:12]3[cH:13][n:14][c:15]([O:18][S:19]([C:20]([F:21])([F:22])[F:23])(=[O:24])=[O:25])[n:16][n:17]23)[cH:7][n:8]1.[CH3:26][O:27][c:28]1[cH:29][c:30]([NH2:41])[cH:31][cH:32][c:33]1[CH:34]1[CH2:35][CH2:36][N:37]([CH3:40])[CH2:38][CH2:39]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[cH:10][cH:11][c:12]3[cH:13][n:14][c:15]([NH:41][c:30]4[cH:29][c:28]([O:27][CH3:26])[c:33]([CH:34]5[CH2:35][CH2:36][N:37]([CH3:40])[CH2:38][CH2:39]5)[cH:32][cH:31]4)[n:16][n:17]23)[cH:7][n:8]1

Participants

3

Reactant 2

HCID 574160883-Methoxy-4-(1-methylpiperidin-4-yl)anilineHCID 86661684Trifluoro-methanesulfonic acid 7-(6-methoxy-pyridin-3-yl)-pyrrolo[2,1-f][1,2,4]triazin-2-yl ester

Product 1

HCID 66711918[3-Methoxy-4-(1-methyl-piperidin-4-yl)-phenyl]-[7-(6-methoxy-pyridin-3-yl)-pyrrolo[2,1-f][1,2,4]triazin-2-yl]-amine

Sources & evidence

ORD record
ord-33d959b3d05e44b0a25f7ec7d08fca67
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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