tert-Butyl 4-(bromomethyl)piperidine-1-carboxylate → Tert-butyl-4-({3-[cyclohexyl(hydroxy)phenylmethyl]-1H-1,2,4-triazol-1-yl}methyl)piperidine-1-carboxylate
Reaction equation
[C:20]([CH3:21])([CH3:22])([CH3:23])[O:24][C:25](=[O:26])[N:27]1[CH2:28][CH2:29][CH:30]([CH2:33][Br:34])[CH2:31][CH2:32]1.[CH:1]1([C:7]([OH:8])([c:9]2[n:10][nH:11][cH:12][n:13]2)[c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1>>[CH:1]1([C:7]([OH:8])([c:9]2[n:10][n:11]([CH2:33][CH:30]3[CH2:29][CH2:28][N:27]([C:25]([O:24][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:26])[CH2:32][CH2:31]3)[cH:12][n:13]2)[c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1Participants
3
Sources & evidence
- ORD record
- ord-c46544a2ab41454285e473c9452fa6c3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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