5-(Difluoromethoxy)-2-methylbenzoic acid → 2-(1-{[5-(Difluoromethoxy)-2-methylphenyl]carbonyl}piperidin-4-yl)-5-(7-methoxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-4-yl)-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one
Reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([C:14]2=[N:18][N:17]([CH:19]3[CH2:20][CH2:21][NH:22][CH2:23][CH2:24]3)[C:16](=[O:25])[C:15]2([CH3:26])[CH3:27])[c:7]2[c:11]1[O:10][C:9]([CH3:12])([CH3:13])[CH2:8]2.[F:28][CH:29]([O:30][c:31]1[cH:32][cH:33][c:34]([CH3:40])[c:35]([C:36](=[O:37])[OH:38])[cH:39]1)[F:41]>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([C:14]2=[N:18][N:17]([CH:19]3[CH2:20][CH2:21][N:22]([C:36]([c:35]4[c:34]([CH3:40])[cH:33][cH:32][c:31]([O:30][CH:29]([F:28])[F:41])[cH:39]4)=[O:37])[CH2:23][CH2:24]3)[C:16](=[O:25])[C:15]2([CH3:26])[CH3:27])[c:7]2[c:11]1[O:10][C:9]([CH3:12])([CH3:13])[CH2:8]2Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-24c7781c649147f3870ce9753cffe446
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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