Dimethylamine → N-{4-[(3-bromophenyl)amino]quinazoline-6-yl}4-(dimethylamino)-2-butenamide
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([NH:8][c:9]2[n:10][cH:11][n:12][c:13]3[cH:14][cH:15][c:16]([NH2:19])[cH:17][c:18]23)[cH:5][cH:6][cH:7]1.[Br:20][C:21](=[CH:22][CH3:23])[C:24]([OH:25])=[O:26].[CH3:27][NH:28][CH3:29].[I:30][c:31]1[cH:32][c:33]([NH:34][c:35]2[c:36]3[c:37]([cH:38][cH:39][c:40]([NH:41][C:49]([CH:50]=[CH:51][CH2:52][N:53]([CH3:54])[CH3:55])=[O:56])[cH:42]3)[n:43][cH:44][n:45]2)[cH:46][cH:47][cH:48]1>>[Br:1][c:2]1[cH:3][c:4]([NH:8][c:9]2[n:10][cH:11][n:12][c:13]3[cH:14][cH:15][c:16]([NH:19][C:49]([CH:50]=[CH:51][CH2:52][N:53]([CH3:54])[CH3:55])=[O:56])[cH:17][c:18]23)[cH:5][cH:6][cH:7]1Participants
5
Sources & evidence
- ORD record
- ord-af1e358e37464f759aaa1503ce54fe03
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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