Dichloromethane → [4-Amino-2-(1-methanesulfonylpiperidin-4-ylamino)thiazol-5-yl]-(2,6-difluorophenyl)methanone
Reaction equation
[CH2:29]([N:30]([CH2:31][CH3:32])[CH:33]([CH3:34])[CH3:35])[CH3:36].[CH3:24][S:25]([Cl:26])(=[O:27])=[O:28].[Cl:37][CH2:38][Cl:39].[NH2:1][c:2]1[n:3][c:4]([NH:17][CH:18]2[CH2:19][CH2:20][NH:21][CH2:22][CH2:23]2)[s:5][c:6]1[C:7](=[O:8])[c:9]1[c:10]([F:16])[cH:11][cH:12][cH:13][c:14]1[F:15]>>[NH2:1][c:2]1[n:3][c:4]([NH:17][CH:18]2[CH2:19][CH2:20][N:21]([S:25]([CH3:24])(=[O:27])=[O:28])[CH2:22][CH2:23]2)[s:5][c:6]1[C:7](=[O:8])[c:9]1[c:10]([F:16])[cH:11][cH:12][cH:13][c:14]1[F:15]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-db70ce0cd29f435182684ab441eab9d8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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