5-{4-[2-(4-Bromo-benzyl)-4-(2,4-dichloro-phenyl)-imidazol-1-yl]-phenyl}-1,2,5-thiadiazolidine-3-one-1,1-dioxide → 5-{-4-[2-(3'-Cyclopentylmethoxy-biphenyl-4-ylmethyl)-4-(2,4-dichloro-phenyl)-imidazol-1-yl]-phenyl}-1,2,5-thiadiazolidine-3-one-1,1-dioxide

HRID 1151305Notes

Reaction equation

HRID 1151305 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][c:7]2[n:8](-[c:20]3[cH:21][cH:22][c:23]([N:26]4[CH2:27][C:28](=[O:33])[NH:29][S:30]4(=[O:31])=[O:32])[cH:24][cH:25]3)[cH:9][c:10](-[c:12]3[c:13]([Cl:19])[cH:14][c:15]([Cl:18])[cH:16][cH:17]3)[n:11]2)[cH:34][cH:35]1.[CH:36]1([CH2:41][O:42][c:43]2[cH:44][c:45]([B:49]([OH:50])[OH:51])[cH:46][cH:47][cH:48]2)[CH2:37][CH2:38][CH2:39][CH2:40]1>>[c:2]1(-[c:45]2[cH:44][c:43]([O:42][CH2:41][CH:36]3[CH2:37][CH2:38][CH2:39][CH2:40]3)[cH:48][cH:47][cH:46]2)[cH:3][cH:4][c:5]([CH2:6][c:7]2[n:8](-[c:20]3[cH:21][cH:22][c:23]([N:26]4[CH2:27][C:28](=[O:33])[NH:29][S:30]4(=[O:31])=[O:32])[cH:24][cH:25]3)[cH:9][c:10](-[c:12]3[c:13]([Cl:19])[cH:14][c:15]([Cl:18])[cH:16][cH:17]3)[n:11]2)[cH:34][cH:35]1

Participants

3

Reactant 2

HCID 593054905-{4-[2-(4-Bromo-benzyl)-4-(2,4-dichloro-phenyl)-imidazol-1-yl]-phenyl}-1,2,5-thiadiazolidine-3-one-1,1-dioxideHCID 613437543-(Cyclopentylmethoxy)phenylboronic acid

Product 1

HCID 593054365-{-4-[2-(3'-Cyclopentylmethoxy-biphenyl-4-ylmethyl)-4-(2,4-dichloro-phenyl)-imidazol-1-yl]-phenyl}-1,2,5-thiadiazolidine-3-one-1,1-dioxide

Sources & evidence

ORD record
ord-7cb73a7f3d2e47ee9cd921e17b123b69
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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