Toluene → 3-[3-(Ethoxycarbonylmethyl-amino)-4-methyl-phenyl]-piperidine-1-carboxylic acid 4-trifluoromethyl-benzyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][NH:6][c:7]1[c:8]([CH3:19])[cH:9][cH:10][c:11]([CH:13]2[CH2:14][NH:15][CH2:16][CH2:17][CH2:18]2)[cH:12]1)=[O:20].[CH3:40][c:41]1[cH:42][cH:43][cH:44][cH:45][cH:46]1.[F:21][C:22]([c:23]1[cH:24][cH:25][c:26]([CH2:27][O:28][C:29](=[O:30])[n:31]2[cH:32][cH:33][n:34][cH:35]2)[cH:36][cH:37]1)([F:38])[F:39]>>[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][NH:6][c:7]1[c:8]([CH3:19])[cH:9][cH:10][c:11]([CH:13]2[CH2:14][N:15]([C:29]([O:28][CH2:27][c:26]3[cH:25][cH:24][c:23]([C:22]([F:21])([F:38])[F:39])[cH:37][cH:36]3)=[O:30])[CH2:16][CH2:17][CH2:18]2)[cH:12]1)=[O:20]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-c8b84f5066ab48bab5af824aad8939a1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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