Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 11515Generated: October 29, 2026

4-[3-(1-Piperidinyl)propoxy]aniline → HCID 178418899, compound

https://huagongshe.com/reaction/11515

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[3-(1-Piperidinyl)propoxy]anilineHCID 21974932—
Reactant5-chloro-3-(hydroxymethylidene)-1H-indol-2-oneHCID 178419036—
ProductHCID 178418899HCID 17841889958%

Reaction Steps

In a manner similar to that described in Example 231, 4-(3-piperidin-1-yl-propoxy)-phenylamine (550 mg, 1.3 equiv.) and 5-chloro-3-hydroxymethylene-1,3-dihydro-indol-2-one (380 mg, 2.00 mmol, 1 equiv.) are reacted to give the named compound as a yellow solid (464 mg, 58%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07098236B2
Source datasetuspto-grants-2006_08
ORD IDord-59c1782dce1341d2b9b6b447e36aac0d
Source noteuspto-grants-2006_08