7-(chloromethyl)-3-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one → 7-({6-Cyclopentyl-4-hydroxy-6-[2-(4-methoxyphenyl)ethyl]-2-oxo-5,6-dihydro-2H-pyran-3-yl}methyl)-3-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one
Reaction equation
[CH:23]1([C:28]2([CH2:36][CH2:37][c:38]3[cH:39][cH:40][c:41]([O:44][CH3:45])[cH:42][cH:43]3)[CH2:29][C:30](=[O:35])[CH2:31][C:32](=[O:34])[O:33]2)[CH2:24][CH2:25][CH2:26][CH2:27]1.[Cl:14][CH2:15][c:16]1[n:17]([CH3:18])[n:19][c:20]([CH3:21])[n:22]1.[Cl:1][CH2:2][c:3]1[n:4][c:5]2[n:6]([c:7](=[O:9])[cH:8]1)[c:10]([CH3:13])[cH:11][s:12]2>>[CH2:2]([c:3]1[n:4][c:5]2[n:6]([c:7](=[O:9])[cH:8]1)[c:10]([CH3:13])[cH:11][s:12]2)[C:31]1=[C:30]([OH:35])[CH2:29][C:28]([CH:23]2[CH2:24][CH2:25][CH2:26][CH2:27]2)([CH2:36][CH2:37][c:38]2[cH:39][cH:40][c:41]([O:44][CH3:45])[cH:42][cH:43]2)[O:33][C:32]1=[O:34]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-3e58f58e5e8d4a2d8e4b284bc51714f1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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