1-{[4-(3-Chloro-4-fluorophenyl)-5-(3-chloro-5-fluorophenyl)-1,3-thiazole-2-yl]carbonyl}imidazolidin-4-one → 1-{[5-(3-Chloro-5-fluorophenyl)-4-(3-chlorophenyl)-1,3-thiazole-2-yl]carbonyl}imidazolidin-4-one

HRID 1151625Notes

Reaction equation

HRID 1151625 reaction equation
[Cl:1][c:2]1[cH:3][c:4](-[c:9]2[n:10][c:11]([C:22](=[O:23])[N:24]3[CH2:25][NH:26][C:27](=[O:29])[CH2:28]3)[s:12][c:13]2-[c:14]2[cH:15][c:16]([Cl:21])[cH:17][c:18]([F:20])[cH:19]2)[cH:5][cH:6][c:7]1[F:8].[Cl:30][c:31]1[cH:32][c:33](-[c:34]2[s:35][c:36]([C:37]([OH:38])=[O:39])[n:40][c:41]2-[c:42]2[cH:43][cH:44][cH:45][c:46]([Cl:47])[cH:48]2)[cH:49][c:50]([F:51])[cH:52]1>>[Cl:1][c:2]1[cH:3][c:4](-[c:9]2[n:10][c:11]([C:22](=[O:23])[N:24]3[CH2:25][NH:26][C:27](=[O:29])[CH2:28]3)[s:12][c:13]2-[c:14]2[cH:15][c:16]([Cl:21])[cH:17][c:18]([F:20])[cH:19]2)[cH:5][cH:6][cH:7]1

Participants

3

Reactant 2

HCID 509428481-{[4-(3-Chloro-4-fluorophenyl)-5-(3-chloro-5-fluorophenyl)-1,3-thiazole-2-yl]carbonyl}imidazolidin-4-oneHCID 708016405-(3-Chloro-5-fluorophenyl)-4-(3-chlorophenyl)-1,3-thiazole-2-carboxylic acid

Product 1

HCID 509429141-{[5-(3-Chloro-5-fluorophenyl)-4-(3-chlorophenyl)-1,3-thiazole-2-yl]carbonyl}imidazolidin-4-one

Sources & evidence

ORD record
ord-f5b64d7854ac4175be0ab2d8fe2eec7d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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