Carbamic acid,n-[2-amino-5-(dimethylamino)-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl ester → {5-Dimethylamino-2-[3-oxo-3-(3-[1,2,4]triazol-4-yl-phenyl)-propionylamino]-4-trifluoromethyl-phenyl}-carbamic acid tert.-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH2:21])[cH:10][c:11]([C:17]([F:18])([F:19])[F:20])[c:12]([N:14]([CH3:15])[CH3:16])[cH:13]1)=[O:22].[CH2:23]([O:25][C:26](=[O:24])[CH2:27][C:28]([c:29]1[cH:30][c:31](-[n:35]2[cH:36][n:37][n:38][cH:39]2)[cH:32][cH:33][cH:34]1)=[O:40])[CH3:41]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH:21][C:26](=[O:25])[CH2:27][C:28]([c:29]2[cH:30][c:31](-[n:35]3[cH:36][n:37][n:38][cH:39]3)[cH:32][cH:33][cH:34]2)=[O:40])[cH:10][c:11]([C:17]([F:18])([F:19])[F:20])[c:12]([N:14]([CH3:15])[CH3:16])[cH:13]1)=[O:22]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-a792a1c4378e49df99d7c20f22ff3bdf
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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