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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1152000Generated: November 3, 2026

Sodium ion → 6-Chloro-2-(2,2,2-trifluoro-ethoxy)-nicotinonitrile

https://huagongshe.com/reaction/1152000

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium ionHCID 923—
ReactantHydroxideHCID 961—
ReactantPyridineHCID 1049—
ReactantAcetonitrileHCID 6342—
ReactantEthyl AcetateHCID 8857—
ReactantPhosphorus oxychlorideHCID 24813—
Reactant6-Chloro-2-(2,2,2-trifluoro-ethoxy)-nicotinamideHCID 57968763—
Product6-Chloro-2-(2,2,2-trifluoro-ethoxy)-nicotinonitrileHCID 86636457—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-1138bede8bf4481da7a4890bfb7ea36c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)