2,5-Difluorobenzoic acid → (7-Fluoro-1-methyl-1,2,3,4-tetrahydrobenzo[e][1,4]diazepin-5-ylidenemethyl)phosphonic acid diethyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][P:4]([O:5][CH2:6][CH3:7])(=[O:8])[CH:9]=[C:10]1[c:11]2[c:12]([cH:18][cH:19][cH:20][cH:21]2)[N:13]([CH3:17])[CH2:14][CH2:15][NH:16]1.[F:22][c:23]1[cH:24][cH:25][c:26]([F:27])[cH:28][c:29]1[C:30]([OH:31])=[O:32]>>[CH2:1]([CH3:2])[O:3][P:4]([O:5][CH2:6][CH3:7])(=[O:8])[CH:9]=[C:10]1[c:11]2[c:12]([cH:18][cH:19][c:20]([F:22])[cH:21]2)[N:13]([CH3:17])[CH2:14][CH2:15][NH:16]1Participants
3
Sources & evidence
- ORD record
- ord-1f85a3ab58584a2488dcb3e74d895888
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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