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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1152735Generated: October 26, 2026

2-[5-chloro-2-[3-(2-methylpiperazin-1-yl)propylamino]pyrimidin-4-yl]-N-methyl-1-benzothiophene-4-carboxamide → N-cyclopropyl-2-[5-methyl-2-[3-(2-methylpiperazin-1-yl)propylamino]pyrimidin-4-yl]-1-benzothiophene-4-carboxamide

https://huagongshe.com/reaction/1152735

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[5-chloro-2-[3-(2-methylpiperazin-1-yl)propylamino]pyrimidin-4-yl]-N-methyl-1-benzothiophene-4-carboxamideHCID 68856125—
ReactantTert-butyl 4-(3-aminopropyl)-3-methylpiperazine-1-carboxylateHCID 68857412—
Reactant2-(2-Chloro-5-methylpyrimidin-4-yl)-benzo[b]thiophene-4-carboxylic acid cyclopropylamideHCID 86625377—
ProductN-cyclopropyl-2-[5-methyl-2-[3-(2-methylpiperazin-1-yl)propylamino]pyrimidin-4-yl]-1-benzothiophene-4-carboxamideHCID 77549750—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-a2997b640e40423cb134c8434f5b44ae
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)