Pyridine → Ro-4987655

HRID 1152823Notes

Reaction equation

[BH3:41].[CH2:48]([Cl:49])[Cl:50].[F:1][c:2]1[c:3]([NH:26][c:27]2[c:28]([F:34])[cH:29][c:30]([I:33])[cH:31][cH:32]2)[c:4]([C:5](=[O:6])[NH:7][O:8][CH2:9][CH2:10][OH:11])[cH:12][c:13]([CH:16]=[N:17][O:18][CH2:19][CH2:20][CH2:21][C:22]([NH:23][CH3:24])=[O:25])[c:14]1[F:15].[OH:42][C:43]([CH:44]([Cl:45])[Cl:46])=[O:47].[n:35]1[cH:36][cH:37][cH:38][cH:39][cH:40]1>>[F:1][c:2]1[c:3]([NH:26][c:27]2[c:28]([F:34])[cH:29][c:30]([I:33])[cH:31][cH:32]2)[c:4]([C:5](=[O:6])[NH:7][O:8][CH2:9][CH2:10][OH:11])[cH:12][c:13]([CH2:16][N:17]2[O:18][CH2:19][CH2:20][CH2:21][C:22]2=[O:25])[c:14]1[F:15]

Participants

Reactant 5

HCID 1049Pyridine

HCID 6331Borane

HCID 6344Dichloromethane

HCID 6597Dichloroacetic Acid

HCID 740200293,4-difluoro-2-(2-fluoro-4-iodoanilino)-N-(2-hydroxyethoxy)-5-[[4-(methylamino)-4-oxobutoxy]iminomethyl]benzamide

Product 1

HCID 11548630Ro-4987655

Sources & evidence

ORD record: ord-badd982b37c24597b0a9292ddf6bbefb
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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