HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-Piperidin-1-yl-ethoxy)-phenylamine → HCID 178418775, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-Piperidin-1-yl-ethoxy)-phenylamine | HCID 3016025 | — |
| Reactant | 5-chloro-3-(hydroxymethylidene)-1H-indol-2-one | HCID 178419036 | — |
| Product | HCID 178418775 | HCID 178418775 | 57% |
Reaction Steps
In a manner similar to that described in Example 231, 4-(2-piperidin-1-yl-ethoxy)-phenylamine (600 mg, 1.2 equiv.) and 5-chloro-3-hydroxymethylene-1,3-dihydro-indol-2-one (444 mg, 2.27 mmol, 1 equiv.) are reacted to give the named compound as a yellow solid (513 mg, 57%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07098236B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-28c01fcc627b48ac80d444d4648e9962 |
| Source note | uspto-grants-2006_08 |