2-(4-Bromophenyl)ethanol → Methyl 5-[4-(2-hydroxyethyl)phenyl]nicotinate

HRID 1153001Notes

Reaction equation

HRID 1153001 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][CH2:9][OH:10])[cH:6][cH:7]1.[CH3:11][C:12]1([CH3:13])[C:14]([CH3:15])([CH3:16])[O:17][B:18]([c:19]2[cH:20][n:21][cH:22][c:23]([C:24](=[O:25])[O:26][CH3:27])[cH:28]2)[O:29]1>>[c:2]1(-[c:19]2[cH:20][n:21][cH:22][c:23]([C:24](=[O:25])[O:26][CH3:27])[cH:28]2)[cH:3][cH:4][c:5]([CH2:8][CH2:9][OH:10])[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 728512-(4-Bromophenyl)ethanolHCID 177502573-(Methoxycarbonyl)pyridine-5-boronic acid, pinacol ester

Product 1

HCID 59606586Methyl 5-[4-(2-hydroxyethyl)phenyl]nicotinate

Sources & evidence

ORD record
ord-30817a2c06e34dff806faf3fdb3b44a0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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