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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1153252Generated: October 25, 2026

Dimethylformamide → 3-(Difluoromethyl)-6-[4-[1-(4-fluorophenyl)ethyl]piperazin-1-yl]-[1,2,4]triazolo[4,3-b]pyridazine

https://huagongshe.com/reaction/1153252

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantDiisopropylethylamineHCID 81531—
Reactant6-Chloro-3-(difluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazineHCID 1472385—
Reactant1-[1-(4-Fluoro-phenyl)-ethyl]-piperazineHCID 4001464—
Product3-(Difluoromethyl)-6-[4-[1-(4-fluorophenyl)ethyl]piperazin-1-yl]-[1,2,4]triazolo[4,3-b]pyridazineHCID 74927502—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-c9e5e25315714d12920b81f303bf11c2
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)