Potassium Cation → 3-[1-(ethylsulfonyl)-4-piperidinyl]-5-(5-{[(1-methylethyl)amino]methyl}-3-pyridinyl)-1H-indole-7-carboxamide

HRID 1153293Notes

Reaction equation

HRID 1153293 reaction equation
[Br:21][c:22]1[cH:23][c:24]2[c:25]([CH:34]3[CH2:35][CH2:36][N:37]([S:40](=[O:41])(=[O:42])[CH2:43][CH3:44])[CH2:38][CH2:39]3)[cH:26][nH:27][c:28]2[c:29]([C:31](=[O:32])[NH2:33])[cH:30]1.[CH3:1][CH:2]([CH3:3])[NH:4][CH2:5][c:6]1[cH:7][n:8][cH:9][c:10]([B:12]2[O:13][C:14]([CH3:15])([CH3:16])[C:17]([CH3:18])([CH3:19])[O:20]2)[cH:11]1.[K+:45].[K+:46].[O-:47][C:48]([O-:49])=[O:50].[O:51]1[CH2:52][CH2:53][O:54][CH2:55][CH2:56]1.[OH2:57]>>[CH3:1][CH:2]([CH3:3])[NH:4][CH2:5][c:6]1[cH:7][n:8][cH:9][c:10](-[c:22]2[cH:23][c:24]3[c:25]([CH:34]4[CH2:35][CH2:36][N:37]([S:40](=[O:41])(=[O:42])[CH2:43][CH3:44])[CH2:38][CH2:39]4)[cH:26][nH:27][c:28]3[c:29]([C:31](=[O:32])[NH2:33])[cH:30]2)[cH:11]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 113844275-bromo-3-[1-(ethanesulfonyl)-4-piperidinyl]-1H-indole-7-carboxamideHCID 57415713N-((5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)methyl)propan-2-amine

Product 1

HCID 577327213-[1-(ethylsulfonyl)-4-piperidinyl]-5-(5-{[(1-methylethyl)amino]methyl}-3-pyridinyl)-1H-indole-7-carboxamide

Sources & evidence

ORD record
ord-8f5e5681843040e580c344fd132709e1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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