Bicarbonate Ion → Tert-butyl 2-[(2,5-difluoro-4-phenylmethoxyphenyl)-hydroxymethyl]morpholine-4-carboxylate
Reaction equation
[BH4-:32].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([C:14]([c:15]2[c:16]([F:30])[cH:17][c:18]([O:22][CH2:23][c:24]3[cH:25][cH:26][cH:27][cH:28][cH:29]3)[c:19]([F:21])[cH:20]2)=[O:31])[O:11][CH2:12][CH2:13]1.[C:34](=[O:35])([OH:36])[O-:37].[CH3:39][OH:40].[Na+:33].[Na+:38]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH:14]([c:15]2[c:16]([F:30])[cH:17][c:18]([O:22][CH2:23][c:24]3[cH:25][cH:26][cH:27][cH:28][cH:29]3)[c:19]([F:21])[cH:20]2)[OH:31])[O:11][CH2:12][CH2:13]1Participants
6
Sources & evidence
- ORD record
- ord-bc1ab0323b7c459685e65395a128d419
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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